Your bloodwork came back fine. So why do you still wake up tired?
Here's what the doctor didn't check: the one molecule that controls your blood flow, your energy, and how you feel when your feet hit the floor.
Dr. Nathan Bryan spent 25 years on it. In 8 questions he'll show you where you're losing it, and the one thing to do first.
8 questions. 2 minutes. No needles. No appointment.
Dr. Nathan S. Bryan — 25+ years of NO research · 100+ peer-reviewed publications · 5 books · Dozens of issued US and international patents
Research Published In
Nature Chemical BiologyPNASCirculationHypertensionFree Radical Biology & Medicine
You already tried
Three pathways make it. The score shows you which one is leaking.
01
Blood vessels
Your age and how much you move. There's an enzyme in your blood vessel wall that makes nitric oxide, and movement is what switches it on. Not workouts. A walk counts. This is the pathway that answers back fastest.
02
Mouth
This is the one almost nobody has heard of. The greens and beets you eat become nitric oxide because of bacteria on your tongue. Rinse with an antiseptic mouthwash every morning and you wipe them out. Published studies show it cuts the signal in your blood. You could be doing everything right and an antiseptic mouthwash is killing it every morning.
03
Holding the signal
Sleep and stress. Short nights and clenched days burn through the signal before it does its job. Age is only one of these three. You can't change it. The other two you can change this week.
"By age 40, we have lost about 50% of our ability to produce nitric oxide in our blood vessels."
Dr. Nathan Bryan, Diary of a CEO, April 2025
That is his interview line. It is not the number this score calculates.
Your Three Pathways
AgeAfter 30
WalksHambrecht '03
PlateKapil '10
RinseTribble '19
HeartBryan '06
NightEverson '05
Day
Acid pillBryan '18
The first sign and symptom of nitric oxide deficiency is usually erectile dysfunction. We call that the canary in the coal mine.
Dr. Nathan Bryan
Diary of a CEO
You cannot destroy the oral microbiome without clinical consequences.
Dr. Nathan Bryan
The Primal Podcast
Nitric oxide is the master signal that tells blood vessels to open, mitochondria to produce energy, and the brain to function at full capacity.
Dr. Nathan Bryan
Deep Wealth Podcast
Without nitric oxide, your body cannot heal.
Dr. Nathan Bryan
Myers Detox Podcast
93% of Americans are metabolically unfit.
Dr. Nathan Bryan
Deep Wealth Podcast
It's the longevity molecule.
Dr. Nathan Bryan
American Muslim Today
If you're killing your oral microbiome and blocking stomach acid, your body can't make nitric oxide -- no matter how healthy your diet is.
Dr. Nathan Bryan
American Muslim Today
🧬
Hold on.
Reading your answers...
Checking your three pathways...
Finding where you're losing it...
Matching your first move.
Your Results
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NO Score
This number is built from your answers across three capacities. It does not measure nitric oxide.
Your first move
Take it again in 14 days. Watch the number move.
We'll send today's score back to you in 14 days, so you can see your before and after side by side.
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Important: These statements have not been evaluated by the FDA. This assessment is educational, not medical advice. N1O1 products are not intended to diagnose, treat, cure, or prevent any disease.